Dr Julian Knight explains how genetic variants modulate gene expression and influence the susceptibility to commom diseases.
Genetic Variation in Inflammation and Immunity
Genetic variation plays an important role in individual susceptibility to common diseases. Dr Julian Knight's research focuses on how genetic variation between individuals affects the way immune and inflammatory genes are expressed. This helps understand genetic susceptibility to common conditions such as infectious, inflammatory or autoimmune diseases, leading to more targeted and effective treatments for patients. Dr Knight recently published a book titled 'Human Genetic Diversity, functional consequences for health and disease'.
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We are all products of our genes, and Genetics is a major focus of NDM research. Our podcasts on genetics look at a variety of projects, including the study of some common and less-common inherited afflictions, as well as the effects our genes can have on disease susceptibility and the efficacy of treatment. Moreover, NDM researchers lead in studying the genetic variation within and between human populations, to understand the similarities and differences between us all.