DNA replication and Cancer
DNA replication and Cancer
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The process of DNA replication is complex, and mistakes can lead to genome instability. Surveillance systems are not always successful which results in mutations that have the potential to inactivate genes or change their activity. This can lead to cancer, and many chemotherapeutic drugs are designed to disrupt DNA replication. A better understanding of these mechanisms can help us develop new drugs with reduced side effects.
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We are all products of our genes, and Genetics is a major focus of NDM research. Our podcasts on genetics look at a variety of projects, including the study of some common and less-common inherited afflictions, as well as the effects our genes can have on disease susceptibility and the efficacy of treatment. Moreover, NDM researchers lead in studying the genetic variation within and between human populations, to understand the similarities and differences between us all.
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