Relevant Links
Translational and Clinical Medicine is the ongoing effort to bring basic science from the bench to the patient, as well as to elucidate safety and effectiveness of the medicines on which we depend. The NDM podcasts on translational and clinical medicine detail our work in this wide-ranging field, from the identification and design of new medicines to clinical trials and trial design and regulation.
| # | Episode Title | Description | People | Date | |
|---|---|---|---|---|---|
| 24 | Creative Commons | Why we work on Alzheimer’s disease | Housed within the Target Discovery Institute, the Alzheimer’s Research UK Oxford Drug Discovery Institute (ODDI) juxtaposes drug discovery expertise alongside scientific and academic understanding of patients, disease mechanisms and model systems. | John Davis | 30 Nov 2016 |
| 23 | X-rays for drug discovery | Dr Frank von Delft works to ensure that X-ray structures can serve as a routine and predictive tool for generating novel chemistry for targeting proteins. | Frank von Delft | 28 Apr 2016 | |
| 22 | Creative Commons | Tracking infections | Professor Derrick Crook from our Experimental Medicine division tells us about his research on tracking infections | Derrick Crook | 08 Feb 2017 |
| 21 | Creative Commons | X-rays for drug discovery | Professor Frank von Delft works to ensure that X-ray structures can serve as a routine and predictive tool for generating novel chemistry for targeting proteins. | Frank von Delft | 23 Sep 2016 |
| 20 | Creative Commons | From information to structure | Dr Brian Marsden aims to make structural and chemical biology data accessible to non-experts, by providing computational resources including data management, sample tracking, in silico modelling support plus provision of public access to SGC data. | Brian Marsden | 02 Jun 2016 |
| 19 | Creative Commons | Unravelling proteins | Dr Nicola Burgess-Brown heads the Biotechnology Group at the SGC, which generates proteins suitable for structural and functional studies. | Nicola Burgess-Brown | 28 Apr 2016 |
| 18 | Creative Commons | Targeting drug discovery | The development of new medicines is dependent on the identification of novel drug targets. | Kilian Huber | 28 Apr 2016 |
| 17 | Creative Commons | Understanding growth signals | Growth hormones and cytokines regulate the key physiological processes of growth and differentiation as well as responses to injury and infection. | Alex Bullock | 27 Apr 2016 |
| 16 | Creative Commons | Inflammation in disease | The main aim of Dr Xue's research is to understand the molecular and cellular mechanisms mediating inflammatory diseases, and to translate their findings into therapeutic concepts to treat these diseases. | Luzheng Xue | 07 Jan 2016 |
| 15 | Creative Commons | A deep breath in | Asthma and COPD (chronic obstructive pulmonary disease) are common conditions that affect the lives of many people. | Mona Bafadhel | 28 Jul 2015 |
| 14 | Creative Commons | Chemistry, epigenetics and drugs | Alteration of gene expression is fundamental to many diseases. A better understanding of how epigenetic proteins affect diseases provides a starting point for therapy development and the discovery of new drug. | Paul Brennan | 28 Jul 2015 |
| 13 | Creative Commons | The genetics of metabolic diseases | A missing step in a metabolic pathway leads to the build-up of toxic compounds, and the lack of materials essential for normal function. | Wyatt Yue | 28 Jul 2015 |
| 12 | Creative Commons | Biological imaging | Video microscopy aims to improve target discovery and drug development and to do so generates large volumes of data. | Jens Rittscher | 09 Feb 2015 |
| 11 | Creative Commons | Pharmacogenomics | Dr Sebastian Nijman develops new approaches to study signalling networks in cancer cells and uncover specific weaknesses, particularly in breast and lung cancer. This can be used to develop more effective drugs and to better guide treatment decisions. | Sebastian Nijman | 09 Feb 2015 |
| 10 | Creative Commons | Asthma | Airway inflammation | Ian Pavord | 10 Dec 2014 |
| 9 | Creative Commons | The Global Health Network | Dr Trudie Lang tells us how the Global Health Network facilitates collaboration and resource sharing. | Trudie Lang | 26 Jun 2013 |
| 8 | Respiratory Medicine | Dr Najib Rahman talks about his research on respiratory medicine. | Najib Rahman | 28 May 2013 | |
| 7 | Creative Commons | Development of chemical probes | Professor Stefan Knapp tells us how the development of chemical probes helps us to find new drugs. | Stefan Knapp | 21 May 2013 |
| 6 | Creative Commons | Drug Discovery | Professor Chas Bountra explains how new drugs can offer novel treatments for neurodegenerative and gastrointestinal diseases, as well as pain disorders. | Chas Bountra | 20 Dec 2010 |
| 5 | Creative Commons | Clinical Trials in Gastroenterology | Dr Simon Travis tells us how clinical trials bring tomorrow's treatments to patients today. | Simon Travis | 25 Mar 2013 |
| 4 | Creative Commons | Proteomics and Biomarkers | Dr Benedikt Kessler tells us how proteomics helps find biomarkers. | Benedikt Kessler | 07 Jun 2011 |
| 3 | Creative Commons | Membrane proteins and drug development | Dr Liz Carpenter talks about her research on membrane proteins and drug development. | Liz Carpenter | 29 Apr 2013 |
| 2 | SHARP | Lowering cholesterol in chronic kidney disease | Colin Baigent | 10 Dec 2014 | |
| 1 | Wider Statin Use Saves Lives | Wider Statin Use Saves Lives | Colin Baigent | 10 Dec 2014 |