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In a series produced by the Oxford Immunology Network, Professor Paul Klenerman talks with colleagues about their recent ground-breaking publications, exploring the original scientific goals, challenges they encountered along the way, and future ambitions in the field. This series will be of interest to anyone studying or working in immunology, medical sciences, biology or related fields.
NB: To Immunity and Beyond is for educational purposes only and should not be considered professional medical advice.
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| # | Episode Title | Description | People | Date | |
|---|---|---|---|---|---|
| 5 | Creative Commons | Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype | Dr Kirsty McHugh and Dr Carolyn Nielsen discuss a recent Cell article: ‘Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype’. | Carolyn Nielsen, Kirsty McHugh, Paul Klenerman | 24 Mar 2025 |
| 4 | Creative Commons | Starvation and infection: The role of sickness-associated anorexia in metabolic adaptation during acute infection | Dr. Barbara Kronsteiner-Dobramysl discusses a recent Metabolism article: ‘Starvation and infection: The role of sickness-associated anorexia in metabolic adaptation during acute infection’. | Kronsteiner-Dobramysl, Paul Klenerman | 27 Feb 2025 |
| 3 | Creative Commons | Optimising CAR-T cell sensitivity by engineering matched extracellular sizes between CAR/antigen and CD2/CD58 adhesion complexes | Professor Omer Dusk discusses a bioRxiv pre-print: ‘Optimising CAR-T cell sensitivity by engineering matched extracellular sizes between CAR/antigen and CD2/CD58 adhesion complexes’. | Omer Dushek, Paul Klenerman | 09 Jan 2025 |
| 2 | Creative Commons | Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis | Professor Quentin Sattentau discusses research published in 'Nature Communications' on the role of enzyme ADAM10 in mediating clearance of apoptotic T cells by macrophages. | Quentin Sattentau, Paul Klenerman | 06 Nov 2024 |
| 1 | Creative Commons | Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations | Professor Astrid Iversen discusses research published in Nature, using historic genome data to investigate the emergence of genetic risk for multiple sclerosis in Northern Europe. | Astrid Iversen, Paul Klenerman | 06 Nov 2024 |